Wang lab researchers develop powerful mouse model to study brain arteriovenous malformations

Wang lab researchers discovered that activation of Notch signaling in the endothelium during brain development causes brain arteriovenous malformations (BAVMs) in mice.  These mice may provide a powerful new tool in which to study BAVMs, which can cause devastating stroke in young people.  This report was published in the August 5 issue of The Proceedings of the National Academy of Sciences.